| ncRNA name | hsa-miR-125b |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell lines HXO-RB44, Y79 and SO-RB50; human RPE cell line ARPE-19; RB samples and adjacent noncancerous tissues |
| Methods | transfection, RT-PCR, MTT assay, scratch wound assay, transwell assay, apoptosis assay, luciferase reporter assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-125b is a suppressor gene miRNA that can promote RB cell proliferation and migration by downregulating the suppressor gene DRAM2. |
| PubMed ID | 27518550 |
| Year | 2016 |
| Title | MicroRNA-125b promotes tumor growth and suppresses apoptosis by targeting DRAM2 in retinoblastoma. |
| Drug-related ncRNA | NO |
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